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How to Diagnose Acute Headache

Acute Headache accounts for about 3-8% of emergency room attendances, and for about 3% of emergency admissions to an acute medical ward.

As a neurologist working in an acute general hospital I would see about 1-2 acute headache cases each week - about 100 per annum.

Almost everyone will experience head pain at some point in their lives, as evidenced by studies of headache epidemiology.

Epidemiology is the who, what and where of medical practice.

Here's a guide on how make a headache diagnosis and sort out the serious from non-serious causes of acute headache. It is based upon a lecture on headache I gave to a Royal College of Physicians of Edinburgh Up-Date Meeting in 2008, 2009, and remains current for 2010.

There are 5 steps to successful headache management:

  1. Take a clinical history and decide which category of headache you are dealing with
  2. Perform a quick, problem orientated neurological examination
  3. Make your differential diagnosis
  4. Arrange brain scans or perform a lumbar puncture procedure
  5. Make a final diagnosis and complete treatment

Step 1: Which acute headache category is it?

When assessing the person with a headache emergency, it is important to realise that there are about 5 different categories of headache that present as an emergency.

  1. Thunderclap Headache
  2. Headache and Fever
  3. Headache with Focal Neurology
    • Visual symptoms
    • Numbness
    • Speech difficulty
    • Weakness
    • Vertigo
    • Epileptic Seizures
    • Confusion

  4. New Onset Persistent Headache
  5. A Previous Headache Disorder that is difficult to control

These 5 categories form the basis of your acute headache differential diagnosis.

Once you have worked out which category you are in you are in a position to start your clinical neurological examination.

Step 2: Perform a Quick Neurological Examination

I have devised a quick screening examination - Forbes Quick Neurological Examination.

In addition to the actions mentioned in the video, look for meningism and check for a Horner's Syndrome.

It goes without saying that you have recored the vital signs of temperature, pulse rate, blood pressure and respiratory rate. If there is altered consciousness a Glasgow Coma Scale should be recorded too.

Step 3: Make a Differential Diagnosis

The differential diagnosis is a term to describe the range of likely diagnoses that could explain the symptoms experienced by the headache sufferer.

The differential diagnosis for each of the 5 categories in Step 1 is slightly different.

Here are the options with the most common first, least common last:

  1. Thunderclap Headache
  2. Headache with fever
    • Systemic Illness Headache
    • Viral Meningitis
    • Acute Sinusitis
    • Bacterial Meningitis
    • Cerebral Abscess
    • Viral Encephalitis

  3. Headache with focal neurology
    • Migraine with aura
    • Cerebrovascular Disease
    • Cerebral tumour
    • Viral Encephalitis

  4. New Onset Persistent Headache
  5. Pre-existing Headache Disorders that are difficult to control
    1. The Neuralgias and Neuralgiform Headaches
      • Ice-pick Headaches
      • Trigeminal Neuralgia
      • Occipital Neuralgia which in most cases is due to cervical spine facet joint disease called cervicogenic headache
      • Supraorbital Neuralgia

    2. Migraine and Cluster Headache
      • Migraine
      • Chronic Migraine
      • Cluster Headache
      • Hemicrania Continua
      • Paroxysmal Hemicrania

Step 4: Arrange Appropriate Investigations

Most people with an acute headache that is not obviously a migraine headache, systemic illness headache, temporal arteritis nor cervicogenic headache will require a brain scan.

A CT Brain Scan is usually sufficient, but there are some pitfalls for the unwary.

There may be rare cases where an MRI Brain Scan is preferable, but MRI needs to be used intelligently, as it is a complex test to set up and perform.

About 30% of people with acute headache will require a lumbar puncture procedure. This is usually to rule out haemorrhage by testing for xanthochromia, but is also needed to rule out high or low intracranial pressure and the presence or absence of infection.

Detailed knowledge of a Lumbar Puncture Procedure is a core skill for any doctor practising emergency medicine.

A poorly performed LP can be a cause of significant patient discomfort and could yield misleading results.

Step 5: Make a Final Headache Diagnosis and Complete Treatment

Based upon data from my own practice, the most common emergency headache diagnoses are primary headache disorders, such as migraine. About 25% of cases had a non-serious secondary headache associated with infection - so callled systemic illness headache.

More detail on headache diagnosis in a typical hospital population is appended.

Only 6% of acute headaches that were admitted to hospital had a life-threatening cause.

The treatment will depend upon your final headache diagnosis.

Read More About Different Headache Types

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