Eosinophilic fasciitis

There is only one case report of eosinophilic fasciitis, co-incidentally from Ireland, as a cause of severe headache. Usually this condition affects the extremities.

This condition underlines to need to palpate the head in clinical examination of headache conditions - local tenderness may indicate a subcutaneous disorder of this sort. A biopsy is needed to confirm the diagnosis of this very, very rare disorder.

Eosinophilis are seen in this microscopic picture of blood cells - the large cells stain for eosin, and the granular inclusions are rich in enzymes such as histaminase and peroxidase. (Creative Commons License, courtesy of Taipei Veterans Hospital)

References

McGuigan C et al. Case report: recurrent temporalis muscle swelling and headache.Neurology. 2003;60(4):724-5.

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